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Link Between Oral Cancer and Tobacco, Alcohol: Expert Shares Preventive Tips

16 April 2025 : Oral cancer, also called mouth cancer, forms in the oral cavity, which includes all parts of your mouth. It is a serious and deadly disease that often goes undiagnosed until it has reached an advanced stage. In an interview with HT Lifestyle, Dr Sanketh K Reddy (BDS, MDS, MSD, DipClSc, MSc, FICO, Apollo Dental Clinic) explained the relation between oral cancer and tobacco and alcohol consumption. Dr Sanketh also highlighted the symptoms and the preventative steps to avoid oral cancer.

The link between tobacco, alcohol, and oral cancer

Dr Sanketh cautioned that tobacco and alcohol consumption increase the risk of oral cancer. “Tobacco smoke contains carcinogenic chemicals like nitrosamines and polycyclic aromatic hydrocarbons (PAHs), while alcohol has solvent effects that increase carcinogen absorption and reduce immune function.”

While alcohol and tobacco could increase the risk of oral cancer, Dr Sanketh added that factors like genetic predisposition, inherited mutations, and family history are also some other risk factors.

He further explained, “Oropharyngeal cancer is linked to viral infections like Human Papillomavirus (HPV), especially HPV-16. Poor fruit and vegetable diet contributes to the risk. Also, long-term exposure to ultraviolet radiation raises the risk of lip cancer, especially in fair-skinned people.”

Summary: Tobacco and alcohol significantly increase the risk of oral cancer. Preventive measures include avoiding these substances, maintaining oral hygiene, and getting regular check-ups for early detection.

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